Translational medicine

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Epidemiological study of chronic degenerative diseases in the adult and elderly population of Brazil.

This investigation includes the various aspects involved in the functionality and burden of chronic diseases, such as social, demographic, environmental, and behavioral risk factors, healthy life expectancy, total mortality, and premature death, morbidity (prevalence and incidence), clinical aspects (diagnosis, severity, response to treatment), and burden of disease YLL – years of life lost, YDL – years lived with disability, – disability-adjusted life years (DALY).YLLYLL– years of life lost,– years of life lost, YDLYDL – years lived with disability, – disability adjusted life years (– years lived with disability, – disability adjusted life years ( DALYDaly).

Check out the Axes:

Axis: Therapy of chronic non-communicable diseases

Development of clinical and preclinical studies of drugs for the treatment and prevention of chronic non-communicable diseases (such as cardiovascular, metabolic, psychiatric, and ophthalmic diseases).

Axis: Pharmacology of pain and inflammation

Characterization of inflammatory and painful changes associated with chronic diseases (diabetes, fibromyalgia, multiple sclerosis, arthritis, and migraine).
Investigation of new biochemical and molecular mechanisms of action in chronic pain treatment (phytotherapeutics, nutraceuticals, and toxins).

Axis: Neuropharmacology

Investigation of new treatments and mechanisms in psychosomatic and neuropsychiatric diseases (depression, anxiety, autism, ADHD).
Characterization of the intestinal microbiota in the involvement and association of neuropsychiatric diseases.

Axis: Wound healing

Involvement of therapies in tissue repair with therapeutic options through Hyperbaric Medicine and other formulations (mineral colloids and biofilms) that provide the repair of chronic wounds.
Involvement of therapies in tissue repair with therapeutic options through Hyperbaric Medicine and other formulations (mineral colloids and biofilms) that provide the repair of chronic wounds.

Axis: Health of the elderly and functionality

Study chronic musculoskeletal diseases and the health of the elderly with a focus on translational and clinical studies applied to Geriatrics.
Development of systematic reviews in health in general.

Axis: Orthopedic health conditions: diagnosis, evaluation and treatment

Main musculoskeletal conditions related to pathophysiology, diagnosis, evaluation strategy, and treatment of translational studies applied to Orthopedics and Geriatrics.
Basic experimental, clinical, methodological, and systematic review studies are developed.

Axis: Ophthalmological diseases

Study the impact of ophthalmological diseases and their repercussions on vision and quality of life.

Axis: Corneal transplantation

Study of different techniques, advantages, and disadvantages for treating corneal blindness.

Axis: Intraocular lenses

Study of different models, optical quality, materials, designs, and biocompatibility.

Axis: Diagnosis and prognosis

Correlation between infectious and parasitic diseases and chronic degenerative/oncological diseases.
Identification of immune response profiles of infectious and parasitic diseases capable of assisting in the diagnosis and prognosis of associated chronic degenerative/oncological diseases in different biological samples.

Axis: Biotechnology applied to the development of new diagnostic kits and vaccines

Identification using biotechnological tools of new biomarkers of infectious and parasitic diseases.
Evaluation of new biomarkers of infectious and parasitic diseases capable of assisting in the diagnosis and prognosis of associated chronic degenerative/oncological diseases.
Development and validation of new immunodiagnostic kits that assist in clinical practice.
Evaluating the preventive vaccine/immunotherapeutic potential of selected infectious and parasitic disease antigens.

Axis: Pain

The initial line of research studies and evaluates degenerative disease of the cervical and lumbar intervertebral disc in the elderly population associated with pain.
Studying and evaluating the impact of pharmacological interventions on pain, with an emphasis on quality of life and muscle performance in humans and the geriatric population.
Implementing the psychometric measures of the instruments used to assess pain, quality of life scales, daily activities, functionality measures, and muscle performance in elderly people with degenerative osteoarticular, muscular, and neurological diseases.

Axis: Neurosciences

Line of research dedicated to validating questionnaires and scales used in research. It studies assessment instruments and pharmacological therapeutic interventions in degenerative and cognitive neurological diseases and dementia, postural instability, and difficulty walking in the elderly.

Axis: Skin healing and keloid treatments

Repair time for chronic wounds and surgical wounds.
Atrophic scars, stretch marks, hypertrophic scars, and keloids.
Wound and scar treatments: dressings, medications, hyperbaric therapy.
Treatments for atrophic, hypertrophic scars and keloids; drugs for topical, systemic, and intralesional use.
Technologies (laser, pulsed light, LED, microneedling, radiofrequency) used in scar and wound treatments.
Wound biology: histological, immunological and molecular aspects.

Axis: Pain and inflammation on the functionality of the elderly

To assess the impact of non-pharmacological interventions on pain, functionality, and muscle performance in elderly animals and humans.
The aim is to measure and verify the impact of exercise-induced myokines and other pro- and anti-inflammatory mediators on pain disorders, immunosenescence, and muscle and functional performance in the elderly.
To verify the psychometric measures of the instruments used to assess pain, functionality, and muscle performance in the elderly with osteoarticular, muscular, and neurological diseases.
To study the multidimensional aspects of the assessment, prevention, and treatment of low back pain in the elderly.

Axis: Strategies for assessing, preventing, and treating health conditions in the elderly

To study the assessment instruments and non-pharmacological therapeutic interventions for cognitive changes and dementia, postural instability, sphincter incontinence, immobility, and family insufficiency in the elderly.
To assess and intervene in the loss of intrinsic capacity, frailty syndrome, and sarcopenia in the elderly.

Axis: Cellular and molecular neuroscience

To research muscle functionality and performance after orthopedic surgeries in the elderly.
To develop studies on osteoporosis, osteosarcopenia, and fragility fractures.

Axis: Clinical neuroscience

Investigate the clinical benefits of new therapeutic interventions for neuropsychiatric diseases.
Investigate clinical and laboratory biomarkers of interest for the diagnosis of neuropsychiatric diseases.

Axis: Cellular and molecular neuroscience

Identify new neural pathways associated with affective and cognitive manifestations of relevance in neuropsychiatric syndromes.
Investigate the potential of procedures based on optical technology (optogenetics) for the therapy of neuropsychiatric diseases.
Investigate the effect of gene therapy on the symptoms of neuropsychiatric diseases.
Investigate the preclinical effects of new treatments for neuropsychiatric diseases.

Axis: Nephropathies and kidney transplantation

Study of chronic kidney disease in all its aspects and stages; treatment modalities: dialysis and transplantation; clinical outcomes after kidney transplantation and risk factors associated with reduced graft and patient survival.

Axis: Role of adipocytokines in ovarian steroidogenesis

1. The main objective of this project is to investigate the role of various adipocytokines in androgen production. vitro using a human adrenal cell line and bovine theca cells.

Axis: In-hospital prognostic factors and mortality in chronic diseases

1. This line aims, through a cohort study, to investigate in individuals over 60 years of age admitted to HUCM, the main nutritional, sociodemographic, and clinical factors related to in-hospital mortality rates, and mortality and readmission.

Amanda Aparecida Oliveira Leopoldino, PhD

Research Axes:
• Health and functionality of the elderly
• Orthopedic health conditions: diagnosis, assessment and treatment

Graduated in Physiotherapy. Master’s, PhD, and Post-Doctorate from the Postgraduate Program in Rehabilitation Sciences at the Federal University of Minas Gerais. Doctoral Internship in Australia, at the University of Sydney. Member of the Rehabilitation Committee of the Fragility Fracture Network FFN Brazil. Researcher at the CNPq NeuroEixo FCMMG group and the multicenter and international research project “Back Complaints in the Elders – BACE” – UFMG. She is the president of Gerontology at SBGG-MG (Management 2023-25).

Profa. Dra. Alessandra Hübner de Souza

Research Axes:
• Therapy of chronic non-communicable diseases
• Pharmacology of pain and inflammation
• Neuropharmacology
• Wound healing

Graduated in Industrial Pharmacy, Master in Toxicological Biochemistry from the Federal University of Santa Maria, PhD and Post-doctorate in Biochemical and Molecular Pharmacology from the Federal University of Minas Gerais (Pharmacology) and Senior Post-doctorate in Medicine from the Pontifical Catholic University of Rio Grande do Sul. Coordinator of the Master in Health Sciences at FCMMG. CNPq Research Productivity Scholarship – 2

Bruno Lovaglio Cançado Trindade, PhD

Research Axes:
• Doenças Oftalmológicas
• Transplante de Córnea
• Doenças Oftalmológicas
• Lente Intraoculares

Graduado em Medicina e residência médica em Oftalmologia pela Clínica de Olhos da Santa Casa de Belo Horizonte. Realizou fellowship em córnea e cirurgia refrativa no Hospital São Geraldo – UFMG, no Massachusetts Eye and Ear Infirmary – Harvard Medical School e no Royal Victorian Eye and Ear Hospital em Melbourne Austrália. Doutor em Oftalmologia pela Universidade Federalk de Minas Gerais, diretor técnico do Instituto de Olhos Ciências Médicas.

Fabio Vasconcellos Comim, PhD

Research Axes:
• Evaluation of macrovascular complications in patients with diabetes mellitus undergoing real replacement therapy and hospitalized
• Role of adipocytokines in ovarian steroidogenesis
• In-hospital prognostic factors and mortality in chronic diseases

He holds a degree in Medicine from the Federal University of Rio Grande do Sul (1994), a medical residency in Internal Medicine and Endocrinology from the Hospital de Clínicas de Porto Alegre (HCPA) (1995-1999), and a master’s degree in Medical Sciences: Endocrinology from the Federal University of Rio Grande do Sul (2003). He completed his PhD abroad with a CAPES scholarship (2007-2011) at Imperial College London, United Kingdom, focusing on polycystic ovary syndrome (PCOS) under the guidance of Prof. Stephen Franks. He is currently an adjunct professor in the Department of Clinical Medicine at the Federal University of Minas Gerais (UFMG) and in the Postgraduate Program in Molecular Medicine at UFMG (Capes score 6) and is the leader of the Research Group on Prevalent Endocrine-Metabolic Diseases at UFMG. He is a professor at the Faculty of Medical Sciences of Minas Gerais, where he works as a collaborator of the Academic Master’s Degree in Health Sciences. Member of the Department of Female Endocrinology, Andrology and Transgenderism (DEFAT) of SBEM. He is an academic editor of the journals PLOS One and Medicine. Topics of interest: microRNAs, hyperandrogenism, polycystic ovary syndrome (PCOS), animal models of PCOS, new markers for diabetic kidney disease, adipocytokines, and bone metabolism.

Fernanda Ludolf Ribeiro, PhD

Research Axes:
• Diagnosis and Prognosis
• Biotechnology applied to the development of new diagnostic kits and vaccines

Graduated in Biological Sciences. Master’s and PhD in Health Sciences from the René Rachou Research Center, in the Cellular and Molecular Parasitology Laboratory. Received 1 year of training in mass spectrometry and proteome at the University of Georgia, US. And 4 months of training in in vitro expression of recombinant proteins and protein microarray at the University of Nottingham, UK. CNPq/FAPEMIG Research Productivity Scholarship – 2.

Fernando Luiz Rolemberg Dantas, PhD

Research Axes:
• Pain
• Neurosciences

Graduated in Medicine from the Federal University of Sergipe (1986), he completed his Residency in Neurosurgery at Santa Casa de Misericórdia de Belo Horizonte. Master in Medicine (Neurosurgery) from the Federal University of São Paulo, PhD in Health Sciences from IAMSPE – Institute of Medical Assistance for State Public Servants – São Paulo, Postdoctorate in Health Sciences (from IAMSPE – Institute of Medical Assistance for State Public Servants of São Paulo). / MG Corresponding Member of the North American Spine Society (NASS). He is currently a Neurosurgeon at Hospital Biocor/Rede DOr in Belo Horizonte and preceptor of the Medical Residency in Neurosurgery at Biocor Institute.

Gisele Viana de Oliveira, PhD

Research Axes:
• Skin healing and keloid treatments

Dr. Gisele Viana de Oliveira is a dermatologist and member of the Brazilian Society of Dermatology, an International Fellow at the American Academy of Dermatology, and a consultant for the Gerson Lehrman Group. She holds a Post Doctoral Fellowship from the University of Texas Medical Branch in Trauma and Burn (2002-2004). She holds a PhD in Cell Biology from the Federal University of Minas Gerais (2005). She holds a Master’s degree in Surgery from the Federal University of Minas Gerais (2000). She holds a degree in Medicine from the Federal University of Minas Gerais (1995). She has experience in Medicine, with an emphasis on Dermatology and Morphology (treatment of scars, wounds, burns, and keloids). Dermatological consultations, diseases, laser treatments, microneedling, pulsed light, cryotherapies, cauterizations, treatments for keloids, burns, wounds and scars. Elected President of the Brazilian Society of Dermatology for the 2023 – 2024 term. She is a professor of the permanent staff of the PPG in Health Sciences at FCMMG and of the APCN for a doctorate submitted to CAPES.

Leani Souza Máximo Pereira, PhD

Research Axes:
• Pain and Inflammation in the Functionality of the Elderly
• Strategies for the Assessment, Prevention, and Treatment of Health Conditions in the Elderly
• Cellular and Molecular Neuroscience

Graduated in Physiotherapy, Master’s and PhD in Biological Sciences (Physiology and Pharmacology) from the Federal University of Minas Gerais and Post-doctorate at The George Institute for Global Health-Sydney University, Australia. Vice-president of the Rehabilitation Committee of the Fragility Fracture Network, FFN. Member of the Pain Committee of the Brazilian Society of Geriatrics and Gerontology-SBGG, Member of the Education Committee of the Brazilian Association of Physiotherapy in Gerontology ABRAFIGE. Leader of the research group/CNPq Studies on Gerontology and Geriatrics. CNPq-1B Productivity Scholarship.

Luiz Alexandre Viana Magno, PhD

Research Axes:
• Clinical neuroscience
• Cellular and molecular neuroscience

He holds a degree in Biomedicine from the State University of Santa Cruz (2009), a PhD in Molecular Medicine from the School of Medicine of the Federal University of Minas Gerais (2012), a postdoctorate in Neurobiology from the Cervo Brain Research Center at Université Laval in Canada (2013), and a postdoctorate in Neuroscience from the School of Medicine of the Federal University of Minas Gerais (2019). He is a permanent professor of the Postgraduate Program in Health Sciences at the School of Medical Sciences of Minas Gerais (FCMMG). He is the coordinator of the FCMMG Animal Facility. He is a professor of the Medicine course at the Prof. Edson Antônio Velano University/Alfenas Foundation for Education and Technology (UNIFENAS/FETA). He is the editor of the Interdisciplinary Journal of Medical Sciences. Member of the Latin American Network for Implementation and Validation of Pharmacogenomic Clinical Guidelines (RELIFAF-CYTED). Leader of the research group “Clinical and Molecular Neuroscience (DGP/CNPq)”. Works in the following lines of research: translational medicine; clinical neuroscience; cellular and molecular neuroscience.

Multidisciplinary Innovation in Health

Cardiovascular Diseases Sciences Applied

sciences-applied-to-cardiovascular-diseases

The selection process for the stricto sensu graduation program at the Faculdade Ciências Médicas de Minas Gerais is structured to identify candidates with solid academic backgrounds and the potential to contribute to scientific production and innovation in the health sector.

Our commitment is to ensure a transparent and rigorous process, valuing professionals who wish to further their studies and develop research aligned with the demands of the sector.

The selection process follows institutional guidelines and CAPES references, ensuring a nationally recognized quality standard.

Admission methods are available for the 1st and 2nd semesters.